Fluticasone Azithromycin And Montelukast (FAM) Therapy In Reducing Corticosteroid Exposure In Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Stem Cell Transplant – A Case Series Of Eight Patients

摘要

BackroundBronchiolitis obliterans syndrome (BOS) is a devastating pulmonary complication affecting long term survivors of allogeneic hematopoietic cell transplantation. Treatment of BOS with prolonged courses of high dose corticosteroids is often associated with significant morbidity. Reducing the exposure to corticosteroids may reduce treatment related morbidity. Our institution has recently begun to treat patients with emerging therapies in an effort to diminish steroid exposure.