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Wood Bark Smoke Induces Lung and Pleural Plasminogen Activator Inhibitor 1 and Stabilizes its mRNA in Porcine Lung Cells

机译：木树皮烟雾诱导肺和胸膜纤溶酶原激活抑制剂1并稳定其在猪肺细胞中的mRNA

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BackgroundWhile aberrant fibrinolysis and plasminogen activator inhibitor-1 (PAI-1) are implicated in ALI, the role of this serpin in the pathogenesis of wood bark smoke (WBS) induced acute lung injury (SIALI) and its regulation in resident lung cells after exposure to smoke is unclear.

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期刊名称 other
作者
Krishna K. Midde; Andriy I. Batchinsky; Leopoldo C. Cancio; Sreerama Shetty; Andrey A. Komissarov; Galina Florova; Kerfoot P. Walker III; Kathy Koenig; Zissis C. Chroneos; Tim Allen; Kevin Chung; Michael Dubick; Steven Idell;
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年(卷),期 -1(36),2
年度 -1
页码 128–137
总页数 26
原文格式 PDF
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Acute lung injury fibrin fibrinolysis serpin smoke inhalation;

机译：急性肺损伤;纤维蛋白;纤维蛋白溶解;丝氨酸蛋白酶抑制剂;吸入烟;

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专利

1. Oncostatin m induces tissue-type plasminogen activator and plasminogen activator inhibitor-1 in calu-1 lung carcinoma cells. [J] . Spence MJ, Streiff R, Day D, Cytokine . 2002,第1期

机译：癌抑制素m在calu-1肺癌细胞中诱导组织型纤溶酶原激活物和纤溶酶原激活物抑制剂-1。
2. Silica Induces Plasminogen Activator Inhibitor-1 Expression through a MAPKs/AP-1-Dependent Mechanism in Human Lung Epithelial Cells. [J] . Toxicology mechanisms and methods . 2008,第7期

机译：二氧化硅通过MAPKs / AP-1依赖性机制诱导人肺上皮细胞中纤溶酶原激活物抑制剂1的表达。
3. ERK5 regulates basic fibroblast growth factor-induced type 1 plasminogen activator inhibitor expression and cell proliferation in lung fibroblasts [J] . Han Jung-Hwa, Hwang Ae-Rang, Nam Dae-Hwan, Life sciences . 2015,第Null期

机译：ERK5调节碱性成纤维细胞生长因子诱导的1型纤溶酶原激活物抑制剂的表达和肺成纤维细胞的增殖
4. Over-activation of the stat3 pathway in lung epithelial cells induces pulmonary inflammation and lung cancer [C] . Liu Yujie, rnPiao Linhua, rnSong Jia, Journal of Organ Dysfunction: ISRD 2007 Abstract Book . 2007

机译：肺上皮细胞中stat3通路的过度激活引起肺部炎症和肺癌
5. Repressive role of stabilized hypoxia inducible factor 1α expression on transforming growth factor β‐induced extracellular matrix production in lung cancer cells [D] . Ando Akira, 安藤啓 2019

机译：稳定的缺氧诱导因子1α表达对肺癌细胞转化生长因子β诱导的细胞外基质产生的抑制作用
6. Translational Research in Acute Lung Injury and Pulmonary Fibrosis: Targeting plasminogen activator inhibitor-1 in tetracycline-induced pleural injury in rabbits [O] . Galina Florova, Ali O. Azghani, Sophia Karandashova, -1

机译：急性肺损伤和肺纤维化的转化研究：针对纤溶酶原激活物抑制剂-1在兔四环素致胸膜损伤中的作用
7. Wood Bark Smoke Induces Lung and Pleural Plasminogen Activator Inhibitor 1 and Stabilizes Its mRNA in Porcine Lung Cells [O] . Krishna K. Midde, Andriy I. Batchinsky, Leopoldo C. Cancio, 2011

机译：木树皮烟雾诱导肺和胸膜纤溶酶原激活抑制剂1，并稳定其在猪肺细胞中的mRNA
8. Wood Bark Smoke Induces Lung and Pleural Plasminogen Activator Inhibitor 1 and Stabilizes Its mRNA in Porcine Lung Cells. [R] . Midde, K. K., Batchinsky, A. I., Cancio, L. C., 2011

机译：木材树皮烟诱导肺和胸膜纤溶酶原激活物抑制剂1并稳定其在猪肺细胞中的mRNa。

Wood Bark Smoke Induces Lung and Pleural Plasminogen Activator Inhibitor 1 and Stabilizes its mRNA in Porcine Lung Cells

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