Highlights of 10 years of immunology in Nature Reviews Immunology

摘要

As Nature Reviews Immunology reaches its 10^th anniversary, we’ve asked the authors of one of the top-cited articles of each year to look back on the state of research at the time their Review was published, to consider why the article has had the impact it has and to discuss the future directions of their field. This Viewpoint article provides an interesting snapshot of some of the fundamental advances in the field of immunology over the past 10 years — including Toll-like receptor signalling, immune regulation mediated by regulatory T cells, indoleamine 2,3-dioxygenase, myeloid-derived suppressor cells and interleukin-10, the development and heterogeneity of macrophages, dendritic cells and T helper cells, and the immune processes involved in diseases such as atherosclerosis — and looks forward to what the next 10 years may bring.