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Plasma and Intracellular Pharmacokinetics of Darunavir/Ritonavir Once Daily and Raltegravir Once and Twice Daily in HIV-Infected Individuals

机译：Darunavir / Ritonavir的血浆和细胞内药代动力学每日一次和RALTEGRAVIR一次和每天两次在艾滋病毒感染的个体中

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摘要

ObjectivesTo investigate the pharmacokinetics of darunavir/ritonavir and raltegravir, in HIV-infected subjects, in both plasma and at the intracellular (IC) site of action.

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期刊名称 other
作者
Akil Jackson; Victoria Watson; David Back; Saye Khoo; Neill Liptrott; Deidre Egan; Keerti Gedela; Chris Higgs; Riaz Abbas; Brian Gazzard; Marta Boffito;
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作者单位

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年(卷),期 -1(58),5
年度 -1
页码 450–457
总页数 14
原文格式 PDF
正文语种
中图分类
关键词
darunavir/ritonavir raltegravir intracellular pharmacokinetics drug interactions;

机译：darunavir / ritonavir;raltegravir;细胞内药代动力学;药物相互作用;

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专利

1. Plasma and intracellular pharmacokinetics of darunavir/ritonavir once daily and raltegravir once and twice daily in HIV-infected individuals. [J] . Jackson A, Watson V, Back D, JAIDS: Journal of acquired immune deficiency syndromes . 2011,第5期

机译：在感染了HIV的个体中，darunavir / ritonavir的血浆和细胞内药代动力学每天一次，而raltegravir每天一次和两次。
2. Intracellular and plasma steady-state pharmacokinetics of raltegravir, darunavir, etravirine and ritonavir in heavily pre-treated HIV-infected patients. [J] . Ter Heine R, Mulder JW, van Gorp EC, British Journal of Clinical Pharmacology . 2010,第5期

机译：在严重感染HIV的患者中，raltegravir，darunavir，etravirine和ritonavir的细胞内和血浆稳态药代动力学。
3. Intracellular and plasma steady-state pharmacokinetics of raltegravir, darunavir, etravirine and ritonavir in heavily pre-treated HIV-infected patients [J] . Rob Ter Heine, Jan Willem Mulder, Eric C. M. Van Gorp, British Journal of Clinical Pharmacology . 2010,第5期

机译：在严重感染HIV的患者中，raltegravir，darunavir，etravirine和ritonavir的细胞内和血浆稳态药代动力学
4. Pharmacokinetics of Cephapirin Sodium in Milk Using an 8-day Extended Therapy Program of Daily Intramammary Infusion in Healthy Lactating Holstein-Friesian Cows [C] . Patrick J. Gorden, Mark van der List, Fred D. Lehman, Annual Meeting of the National^Mastitis^Council . 2013

机译：用8天延长治疗牛奶中Cephapirin钠的药代动力学，使用8天延长治疗健康哺乳酸荷斯坦 - 摩泽 - 奶牛
5. Validation of a UPLC-MS/MS method for the simultaneous measurement of the antiretroviral drugs atazanavir, darunavir, efavirenz, etravirine, lopinavir, raltegravir, ritonavir from human plasma. [D] . Patel, Rutva. 2012

机译：用于从人血浆中同时测定抗逆转录病毒药物阿扎那韦，达鲁那韦，依非韦伦，依曲韦林，洛匹那韦，拉格列韦，利托那韦的UPLC-MS / MS方法的验证。
6. Intracellular and plasma steady-state pharmacokinetics of raltegravir darunavir etravirine and ritonavir in heavily pre-treated HIV-infected patients [O] . Rob ter Heine, Jan Willem Mulder, Eric C M van Gorp, 2010

机译：在严重感染HIV的患者中raltegravirdarunaviretravirine和ritonavir的细胞内和血浆稳态药代动力学
7. Intracellular and plasma steady-state pharmacokinetics of raltegravir, darunavir, etravirine and ritonavir in heavily pre-treated HIV-infected patients [O] . ter Heine, Rob, Mulder, Jan Willem, van Gorp, Eric C M, 2010

机译：预先大量治疗的HIV感染患者中raltegravir，darunavir，etravirine和ritonavir的细胞内和血浆稳态药代动力学

Plasma and Intracellular Pharmacokinetics of Darunavir/Ritonavir Once Daily and Raltegravir Once and Twice Daily in HIV-Infected Individuals

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