High frequency stimulation can suppress globally seizures induced by 4-AP in the rat hippocampus: An acute in vivo study

摘要

BackgroundHigh frequency stimulation (HFS) on the hippocampus can locally suppress epileptiform activity in-vitro and decrease seizure frequency in vivo. In-vitro HFS on the ventral commissural tract, a novel target, was shown to block the axonal conduction and suppress activity in the CA1 and CA3 neuron.