Copper-64 radiolabeling and biological evaluation of bifunctional chelators for radiopharmaceutical development Evaluation of 64Cu-bifunctional chelators

摘要

IntroductionThe development of novel bifunctional chelates for attaching copper-64 to biomolecules has been an active area of research for several years. However, many of these ⁶⁴Cu-chelates have poor in vivo stability or harsh radiolabeling conditions.