Proteins of the VEGFR and EGFR pathway as predictive markers for adjuvant treatment in patients with stage II/III colorectal cancer: results of the FOGT-4 trial

机译：VEGFR和EGFR通路的蛋白作为II / III期结直肠癌患者辅助治疗的预测标志物：FOGT-4试验的结果

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BackgroundUnlike metastatic colorectal cancer (CRC) there are to date few reports concerning the predictive value of molecular biomarkers on the clinical outcome in stage II/III CRC patients receiving adjuvant chemotherapy. Aim of this study was to assess the predictive value of proteins related with the EGFR- and VEGFR- signalling cascades in these patients.

机译：背景技术与转移性大肠癌（CRC）相比，迄今为止，关于分子生物标记物对接受辅助化疗的II / III期CRC患者临床预后的预测价值的报道很少。这项研究的目的是评估与这些患者中EGFR和VEGFR信号传导级联反应相关的蛋白质的预测价值。

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期刊名称 Journal of Experimental Clinical Cancer Research : CR
作者
Thomas Thomaidis; Annett Maderer; Andrea Formentini; Susanne Bauer; Mario Trautmann; Michael Schwarz; Wiebke Neumann; Jens Martin Kittner; Arno Schad; Karl-Heinrich Link; Johannes Wilhelm Rey; Arndt Weinmann; Arthur Hoffman; Peter Robert Galle; Marko Kornmann; Markus Moehler;
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年(卷),期 2014(33),1
年度 2014
页码 83
总页数 11
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
Stage II/III colorectal cancer Predictive biomarkers EGFR VEGFR Amphiregulin Epiregulin PTEN Hif-1 alpha Adjuvant chemotherapy;

机译：II / III期大肠癌;预测性生物标志物;EGFR;VEGFR;双调蛋白;上皮调节蛋白;PTEN;Hif-1 alpha;辅助化疗;

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专利

1. Proteins of the VEGFR and EGFR pathway as predictive markers for adjuvant treatment in patients with stage II/III colorectal cancer: results of the FOGT-4 trial [J] . Thomas Thomaidis, Annett Maderer, Andrea Formentini, Journal of experimental & clinical cancer research : . 2014,第1期

机译：VEGFR和EGFR通路的蛋白作为II / III期大肠癌患者辅助治疗的预测标志物：FOGT-4试验的结果
2. Matrix metalloproteinase 7 is a useful marker for 5-fluorouracil-based adjuvant chemotherapy in stage II and stage III colorectal cancer patients [J] . Yong Huang, Haijun Yu, Han Lei Conghua Xie, Medical oncology . 2014,第3期

机译：基质金属蛋白酶7是II期和III期大肠癌患者基于5-氟尿嘧啶的辅助化疗的有用标志物
3. Impact of age on the use of adjuvant treatments in patients undergoing surgery for colorectal cancer: patients with stage III colon or stage II/III rectal cancer [J] . C. Sarasqueta, the REDISECC-CARESS/CCR group, A. Perales, BMC Cancer . 2019,第1期

机译：在接受结直肠癌患者的患者中使用佐剂治疗的影响：III阶段结肠或阶段II / III直肠癌的患者
4. Determination of EGFR and VEGF signaling pathway activity by immuno-MALDI to predict the outcome of targeted colorectal cancer (CRC) treatment [C] . Robert Popp, Andrew G. Chambers, Adriana Aguilar-Mahecha, ASMS Conference on Mass Spectrometry and Allied Topics . 2015

机译：免疫马尔迪的EGFR和VEGF信号通路活性预测靶向结直肠癌（CRC）治疗的结果
5. The Association of Hospital and Patient Characteristics with Treatment Initiation among Veterans with Stage I, II, or III Lung, Colon or Rectal Cancer [D] . Clary, Alecia S. 2019

机译：具有阶段I，II或III肺，结肠或直肠癌的退伍军人治疗发起的医院和患者特征
6. Impact of age on the use of adjuvant treatments in patients undergoing surgery for colorectal cancer: patients with stage III colon or stage II/III rectal cancer [O] . C. Sarasqueta, A. Perales, A. Escobar, 2019

机译：年龄对接受结直肠癌手术的患者使用辅助治疗的影响：III期结肠癌或II / III期直肠癌患者
7. Proteins of the VEGFR and EGFR pathway as predictive markers for adjuvant treatment in patients with stage II/III colorectal cancer: results of the FOGT-4 trial [O] . Thomas Thomaidis, Annett Maderer, Andrea Formentini, 2014

机译：VEGFR和EGFR通路的蛋白作为II / III期大肠癌患者辅助治疗的预测标志物：FOGT-4试验的结果

Proteins of the VEGFR and EGFR pathway as predictive markers for adjuvant treatment in patients with stage II/III colorectal cancer: results of the FOGT-4 trial

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