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The link between Family History and risk of Type 2 Diabetes is Not Explained by Anthropometric Lifestyle or Genetic Risk Factors: the EPIC-InterAct Study

机译:人体测量生活方式或遗传危险因素未解释家庭历史与2型糖尿病风险之间的联系:史诗 - 互动研究

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摘要

Aims/hypothesisAlthough family history of type 2 diabetes (T2D) is a strong risk factor for the disease, the factors mediating this excess risk are poorly understood. In the InterAct case-cohort study we investigated the association of family history of diabetes among different family members with incidence of T2D and the extent to which genetic, anthropometric and lifestyle risk factors mediated this association.
机译:目的/假设尽管2型糖尿病(T2D)的家族病史是该疾病的重要危险因素,但对于这种过度危险的介导因素知之甚少。在InterAct病例队列研究中,我们调查了不同家庭成员之间的糖尿病家族史与T2D发病率的关系,以及遗传,人体测量学和生活方式风险因素介导这种关系的程度。

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