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Apocynin-Treatment Reverses Hyperoxaluria Induced Changes in NADPH Oxidase System Expression in Rat Kidneys: A Transcriptional Study

机译：夹竹桃治疗逆转高草酸尿症引起的变化在大鼠肾脏NaDpH氧化酶系统中的表达：转录研究

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PurposeWe have previously shown that production of reactive oxygen species (ROS) is an important contributor to renal injury and inflammation following exposure to oxalate (Ox) or calcium-oxalate (CaOx) crystals. The present study was conducted, utilizing global transcriptome analyses, to determine the effect of Apocynin on changes in the NADPH oxidase system activated in kidneys of rats fed a diet leading to hyperoxaluria and CaOx crystal deposition.

机译：目的我们以前已经表明，在暴露于草酸盐（Ox）或草酸钙（CaOx）晶体后，活性氧（ROS）的产生是肾脏损伤和炎症的重要原因。本研究是利用整体转录组分析进行的，以确定Apocynin对饲喂导致高草酸尿症和CaOx晶体沉积的大鼠肾脏中激活的NADPH氧化酶系统变化的影响。

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期刊名称 other
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Sunil Joshi; Benjamin T. Saylor; Wei Wang; Ammon B. Peck; Saeed R. Khan;
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年(卷),期 -1(7),10
年度 -1
页码 e47738
总页数 11
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专利

1. Effect of NADPH oxidase inhibition on the expression of kidney injury molecule and calcium oxalate crystal deposition in hydroxy-L-proline-induced hyperoxaluria in the male Sprague-Dawley rats. [J] . Zuo J, Khan A, Glenton PA, Nephrology, dialysis, transplantation: official publication of the European Dialysis and Transplant Association - European Renal Association . 2011,第6期

机译：NADPH氧化酶抑制作用对雄性Sprague-Dawley大鼠肾脏损伤分子表达和草酸钙结晶沉积的作用是羟基L-脯氨酸引起的高草酸尿症。
2. Effect of NADPH oxidase inhibition on the expression of kidney injury molecule and calcium oxalate crystal deposition in hydroxy-L-proline-inducedn hyperoxaluria in the male Sprague–Dawley rats [J] . Saeed R. Khan Nephrology Dialysis Transplantation . 2011,第6期

机译：NADPH氧化酶抑制作用对雄性Sprague–Dawley大鼠肾损伤分子表达和草酸钙结晶的影响
3. Nebivolol prevents ethanol-induced reactive oxygen species generation and lipoperoxidation in the rat kidney by regulating NADPH oxidase activation and expression [J] . do Vale Gabriel T., Gonzaga Natalia A., Simplicio Janaina A., European Journal of Pharmacology: An International Journal . 2017,第期

机译：Nebivolol通过调节NADPH氧化酶活化和表达，通过调节乙醇诱导的乙醇诱导的反应性氧物质产生和脂氧化脂肪氧化
4. The Role of NADPH Oxidase on L-NAME-Induced Leukocyte-Endothelial Interactions in Rat Mesenteric Postcapillary Venules [C] . Hung T. Pham, Robert Barsotti, Amber N. Koon American Peptide Symposium . 2013

机译：NADPH氧化酶在大鼠肠系膜后静脉静脉中L-名称诱导的白细胞 - 内皮相互作用的作用
5. Reduction of Angiotensin II Induced Hypertension and Cardiac Fibrosis with GLP-1 Receptor Agonist and DPP-4 Inhibitor via Decreasing NADPH Oxidase Expression [D] . Banks, Trenton Edward. 2020

机译：通过降低NADPH氧化酶表达，通过降低NADPH-1受体激动剂和DPP-4抑制剂减少血管紧张素II诱导的高血压和心肌纤维化
6. Effect of NADPH oxidase inhibition on the expression of kidney injury molecule and calcium oxalate crystal deposition in hydroxy-L-proline-induced hyperoxaluria in the male Sprague–Dawley rats [O] . Jian Zuo, Aslam Khan, Patricia A. Glenton, -1

机译：NADPH氧化酶抑制对Sprague–Dawley雄性大鼠羟基L-脯氨酸诱导的高草酸尿中肾损伤分子表达和草酸钙晶体沉积的影响
7. Apocynin-treatment reverses hyperoxaluria induced changes in NADPH oxidase system expression in rat kidneys: a transcriptional study. [O] . Sunil Joshi, Benjamin T Saylor, Wei Wang, 2012

机译：apocynin治疗可逆转高草酸尿引起的大鼠肾脏NaDpH氧化酶系统表达的变化：一项转录研究。

Apocynin-Treatment Reverses Hyperoxaluria Induced Changes in NADPH Oxidase System Expression in Rat Kidneys: A Transcriptional Study

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