The plant alkaloid tetrandrine inhibits metastasis via autophagy-dependent Wnt/β-catenin and metastatic tumor antigen 1 signaling in human liver cancer cells

机译：植物生物碱粉防己碱通过自噬依赖性Wnt /β-catenin和转移性肿瘤抗原1信号转导抑制肝癌细胞的转移

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BackgroundTetrandrine is a bisbenzylisoquinoline alkaloid isolated from the Chinese medicinal herb Stephania tetrandra S. Moore. We previously demonstrated that tetrandrine exhibits potent antitumor effects in many types of cancer cells. In this study, we investigated the effects of tetrandrine on human hepatocellular carcinoma (HCC) metastasis.

机译：背景粉防己碱是从中草药Stephania tetrandra S.Moore中分离出来的双苄基异喹啉生物碱。我们先前证明粉防己碱在许多类型的癌细胞中均表现出强大的抗肿瘤作用。在这项研究中，我们调查了粉防己碱对人肝细胞癌（HCC）转移的影响。

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期刊名称 Journal of Experimental Clinical Cancer Research : CR
作者
Zhenxing Zhang; Ting Liu; Man Yu; Kangdi Li; Wenhua Li;
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作者单位

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年(卷),期 2018(37),-1
年度 2018
页码 7
总页数 11
原文格式 PDF
正文语种
中图分类肿瘤学;
关键词
Autophagy Metastasis MTA1 Tetrandrine Wnt/β-catenin Epithelial-Mesenchymal transition (EMT);

机译：自噬;转移;MTA1;粉防己碱;Wnt /β-catenin;上皮-间质转化（EMT）;

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专利

1. The plant alkaloid tetrandrine inhibits metastasis via autophagy-dependent Wnt/β-catenin and metastatic tumor antigen 1 signaling in human liver cancer cells [J] . Zhenxing Zhang, Ting Liu, Man Yu, Journal of experimental & clinical cancer research : . 2018,第1期

机译：植物生物碱粉防己碱通过自噬依赖性Wnt /β-catenin和转移性肿瘤抗原1信号传导抑制人肝癌细胞的转移
2. Tetrandrine inhibits Wnt/beta-catenin signaling and suppresses tumor growth of human colorectal cancer. [J] . He BC, Gao JL, Zhang BQ, Molecular pharmacology. . 2011,第2期

机译：粉防己碱抑制Wnt /β-catenin信号传导并抑制人大肠癌的肿瘤生长。
3. Antrodia camphorata inhibits metastasis and epithelial-to-mesenchymal transition via the modulation of claudin-1 and Wnt/β-catenin signaling pathways in human colon cancer cells [J] . You-Cheng Hseu, Yu-Hsien Chao, Kai-Yuan Lin, Journal of Ethnopharmacology: An Interdisciplinary Journal Devoted to Bioscientific Research on Indigenous Drugs . 2017,第期

机译：Antrodia Camphorata通过在人结肠癌细胞中调节Claudin-1和Wnt /β-catenin信号传导途径来抑制转移和上皮对间充质转化
4. IMPACT OF MASITINIB ON METASTATIC MAST CELL TUMORS AND ON THE EMERGENCE OF METASTASIS FROM NON-METASTATIC TUMORS [C] . Olivier Hermine Annual Conference of the Veterinary Cancer Society . 2009

机译：Masitinib对非转移性肿瘤转移肥大细胞肿瘤的影响及转移的出现
5. Targeting human acute myelogenous leukemia by inhibiting aberrant Wnt/beta-catenin signaling. [D] . Kim, Eleanor. 2014

机译：通过抑制异常的Wnt /β-catenin信号传导靶向人类急性粒细胞性白血病。
6. Tetrandrine Inhibits Wnt/β-Catenin Signaling and Suppresses Tumor Growth of Human Colorectal Cancer [O] . Bai-Cheng He, Jian-Li Gao, Bing-Qiang Zhang, -1

机译：粉防己碱抑制Wnt /β-Catenin信号传导并抑制大肠癌的肿瘤生长
7. The plant alkaloid tetrandrine inhibits metastasis via autophagy-dependent Wnt/β-catenin and metastatic tumor antigen 1 signaling in human liver cancer cells [O] . Zhenxing Zhang, Ting Liu, Man Yu, 2018

机译：植物生物碱Tetrandrine通过自噬依赖性Wnt /β-catenin和转移肿瘤抗原1信号传导在人肝癌细胞中抑制转移

The plant alkaloid tetrandrine inhibits metastasis via autophagy-dependent Wnt/β-catenin and metastatic tumor antigen 1 signaling in human liver cancer cells

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