Assessing the Efficacy of Endoscopic Office Olfactory Biopsy Sites to Produce Neural Progenitor Cell Cultures for the Study of Neuropsychiatric Disorders

摘要

IntroductionThe olfactory region is capable of continuous neurogenesis. Situated on the cribriform plate and segments of the superior septum and both superior and middle turbinates, it is accessible through office-based biopsy and can be used to generate neural progenitor cells to study molecular abnormalities associated with neuropsychiatric disorders.The purpose of the study was to evaluate the efficacy of the endoscopic office olfactory biopsy from middle turbinate and superior-posterior septum to produce the neural progenitor cells.