Aerobic Oxidative Heck/Dehydrogenation Reactions of Cyclohexenones: Efficient Access to meta-Substituted Phenols

摘要

A new dicationic Pd^II catalyst, employing a 6,6'-dimethylbipyridine ligand, has been identified that is capable of promoting both aerobic oxidative Heck coupling and dehydrogenation reactions of cyclohexenones. These reactions may be combined in a one-pot sequence to enable the straightforward synthesis of meta-substituted phenols.