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UNDERSTANDING HETEROGENEITY IN PTSD: FEAR DYSPHORIA AND DISTRESS

机译:理解创伤后应激障碍的异质性:恐惧烦恼和痛苦

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摘要

Fear, dysphoria, and distress are prominent components in the conceptualization of posttraumatic stress disorder (PTSD). However, because our diagnostic categories are open concepts, relying on observed patterns of symptoms for classification, it is unclear whether these components represent core or auxiliary features of the disorder. Convergence across multiple indices is critical for this understanding. In this paper, we examine these components of PTSD across observed symptom patterns, broader theoretical conceptualizations, underlying information processing mechanisms of attention and memory, and underlying learning and neurobiological mechanisms. For each, evidence for similarity or distinctiveness of PTSD with other anxiety disorders and depression is examined. Throughout the review, key points of similarity to the anxiety disorders and divergence with depression argue for a distinction between core fear symptoms and auxiliary dysphoria and distress symptoms. Implications are discussed, noting that, as heterogeneity increases, core characteristics will become more diffused and ancillary constructs will gain an inflated degree of importance.
机译:恐惧,烦躁不安和困扰是创伤后应激障碍(PTSD)概念的重要组成部分。但是,由于我们的诊断类别是开放概念,依赖于观察到的症状模式进行分类,因此尚不清楚这些成分是否代表该疾病的核心特征或辅助特征。多个索引之间的收敛对于这种理解至关重要。在本文中,我们通过观察到的症状模式,更广泛的理论概念,注意力和记忆的潜在信息处理机制以及潜在的学习和神经生物学机制,研究了PTSD的这些组成部分。对于每一种,都检查了PTSD与其他焦虑症和抑郁症的相似性或独特性的证据。在整个审查过程中,与焦虑症和抑郁症的相似之处关键在于核心恐惧症状与辅助烦躁不安和困扰症状之间的区别。讨论了一些影响,并指出,随着异质性的增加,核心特征将变得更加分散,辅助构造的重要性将日益提高。

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