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Candidate gene approach to identifying rare genetic variants associated with lone atrial fibrillation

机译：候选基因方法鉴定与孤立性房颤相关的罕见遗传变异

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摘要

BACKGROUNDRare variants in candidate atrial fibrillation (AF) genes have been associated with AF in small kindreds. The extent to which such polymorphisms contribute to AF is unknown.

机译：背景候选心房纤颤（AF）基因中的罕见变体已与小亲戚的AF相关。这种多态性对AF的贡献程度尚不清楚。

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期刊名称 other
作者
Peter Weeke; Babar Parvez; Marcia Blair; Laura Short; Christie Ingram; Gayle Kucera; Tanya Stubblefield; Dan M. Roden;
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作者单位

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年(卷),期 -1(11),1
年度 -1
页码 46–52
总页数 13
原文格式 PDF
正文语种
中图分类
关键词
Atrial fibrillation arrhythmia Candidate genes Family study Genetic variation Genetic epidemiology Proarrhythmia Rare variants;

机译：心房颤动心律失常;候选基因;家族研究;遗传变异;遗传流行病学;心律失常;罕见变异;

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专利

1. Candidate gene approach to identifying rare genetic variants associated with lone atrial fibrillation [J] . WeekeP., ParvezB., BlairM., Heart rhythm: the official journal of the Heart Rhythm Society . 2014,第1期

机译：候选基因方法鉴定与孤立性房颤相关的罕见遗传变异
2. Very early-onset lone atrial fibrillation patients have a high prevalence of rare variants in genes previously associated with atrial fibrillation [J] . OlesenM.S., AndreasenL., JabbariJ., Heart rhythm: the official journal of the Heart Rhythm Society . 2014,第2期

机译：极早期发作的孤立性房颤患者中以前与房颤相关的基因中罕见变异的患病率很高
3. Genetic variants on chromosomes 7p31 and 12p12 are associated with abnormal atrial electrical activation in patients with early‐onset lone atrial fibrillation [J] . Seifert Mariam B., Olesen Morten S., Christophersen Ingrid E., Annals of noninvasive electrocardiology: the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc . 2019,第6期

机译：染色体7p31和12p12上的遗传变体与早发孤房纤维化患者的患者异常的心房电激活有关
4. A Genetic Programming Approach for Classification of the Spontaneous Termination of Atrial Fibrillation [C] . O. Valenzuela, F. Rojas, I. Rojas, International Conference on Bioinformatics and Computational Biology . 2007

机译：对心房颤动自发终止分类的遗传编程方法
5. An in vivo functional genomics approach to identify and characterize pathological genetic variants. [D] . Templeton, Amanda Kaye. 2016

机译：一种体内功能基因组学方法，用于鉴定和表征病理性遗传变异。
6. Examining Rare and Low-Frequency Genetic Variants Previously Associated with Lone or Familial Forms of Atrial Fibrillation in an Electronic Medical Record System: A Cautionary Note [O] . Peter Weeke, Joshua C. Denny, Lisa Basterache, -1

机译：在电子病历系统中检查以前与房颤的单发或家族性形式相关的稀有和低频遗传变异：警示
7. Candidate gene approach to identifying rare genetic variants associated with lone atrial fibrillation [O] . Peter Weeke, Babar Parvez, Marcia Blair, 2014

机译：候选基因鉴定孤房纤维化相关稀有遗传变异的方法

Candidate gene approach to identifying rare genetic variants associated with lone atrial fibrillation

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