Fontan Hemodynamics from 100 Patient-Specific Cardiac Magnetic Resonance Studies: A Computational Fluid Dynamics Analysis

摘要

Objectives:This study sought to quantify average hemodynamic metrics of the Fontan connection as reference for future investigations, compare connection types (intra-atrial vs. extracardiac) and identify functional correlates using computational fluid dynamics (CFD) in a large patient-specific cohort. Fontan hemodynamics, particularly power losses, are hypothesized to vary considerably among single ventricle patients and adversely affect systemic hemodynamics and ventricular function if sub-optimal.