Serum Inflammatory Markers and Risk of Colorectal Cancer in Patients with Inflammatory Bowel Diseases

摘要

IntroductionPatients with inflammatory bowel diseases (IBD; Crohn’s disease (CD), ulcerative colitis (UC)) are at increased risk of colorectal cancer (CRC). Persistent inflammation is hypothesized to increase risk of CRC in patients with IBD; however the few studies in this area have been restricted to cross-sectional assessments of histologic severity. No prior studies have examined association between C-reactive protein or erythrocyte sedimentation rate (ESR) elevation and risk of CRC in an IBD cohort.