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Prenatal Exposure to Airborne Polycyclic Aromatic Hydrocarbons and IQ: Estimated Benefit of Pollution Reduction

机译:产前暴露于空气中的多环芳烃和智商:减少污染的估计效益

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摘要

Outdoor air pollution, largely from fossil fuel burning, is a major cause of morbidity and mortality in the U. S., costing billions of dollars every year in health care and loss of productivity. The developing fetus and young child are especially vulnerable to neurotoxicants, such as polycyclic aromatic hydrocarbons (PAH) released to ambient air by combustion of fossil fuel and other organic material. Low income populations are disproportionately exposed to air pollution. Based on the results of a prospective cohort study in a low-income population in New York City (NYC) that found a significant inverse association between child IQ and prenatal exposure to airborne PAH, we estimated the increase in IQ and related lifetime earnings in a low income urban population as a result of a hypothesized modest reduction of ambient PAH concentrations in NYC of .25 ng/m3. For reference, the current estimated annual mean PAH concentration is~ 1 ng/m3. Restricting to NYC Medicaid births and using a 5% discount rate, we estimated the gain in lifetime earnings due to IQ increase for a single year cohort to be $215 million (best estimate). Using much more conservative assumptions, the estimate was $43 million. This analysis suggests that a modest reduction in ambient concentrations of PAH is associated with substantial economic benefits to children.
机译:在美国,室外空气污染主要来自化石燃料燃烧,这是发病率和死亡率的主要原因,每年在医疗保健和生产力损失上造成数十亿美元的损失 。发育中的胎儿和幼儿特别容易受到神经毒物的伤害,例如通过化石燃料和其他有机材料的燃烧释放到周围空气中的多环芳烃(PAH)。低收入人群遭受空气污染的比例过高。根据一项针对纽约市(NYC)低收入人群的前瞻性队列研究结果,该结果发现儿童智商与机载PAH的产前暴露之间存在显着的负相关关系,我们估算了智商和相关终身收入的增长假设纽约市的环境PAH浓度适度降低了.25 ng / m 3 ,从而导致城市低收入人群。作为参考,目前估计的年平均PAH浓度约为1 ng / m 3 。考虑到纽约市医疗补助计划的出生,并使用5%的折现率,我们估计单年度队列智商增加所带来的终生收入为2.15亿美元(最佳估计)。使用更加保守的假设,估计为4300万美元。该分析表明,环境中PAH浓度的适度降低会给儿童带来可观的经济利益。

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