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Polymorphisms in the Inflammatory Pathway Genes TLR2 TLR4 TLR9 LY96 NFKBIA NFKB1 TNFA TNFRSF1A IL6R IL10 IL23R PTPN22 and PPARG Are Associated with Susceptibility of Inflammatory Bowel Disease in a Danish Cohort

机译：炎症队列基因TLR2TLR4TLR9LY96NFKBIANFKB1TNFATNFRSF1AIL6RIL10IL23RPTPN22和PPARG的多态性与丹麦人群中炎症性肠病的易感性相关

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BackgroundThe inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis (UC), result from the combined effects of susceptibility genes and environmental factors. Polymorphisms in genes regulating inflammation may explain part of the genetic heritage.

机译：背景炎症性肠病（IBD），克罗恩病（CD）和溃疡性结肠炎（UC）是易感基因和环境因素共同作用的结果。调节炎症的基因中的多态性可以解释部分遗传遗传。

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作者
Steffen Bank; Paal Skytt Andersen; Johan Burisch; Natalia Pedersen; Stine Roug; Julie Galsgaard; Stine Ydegaard Turino; Jacob Broder Brodersen; Shaista Rashid; Britt Kaiser Rasmussen; Sara Avlund; Thomas Bastholm Olesen; Hans Jürgen Hoffmann; Marianne Kragh Thomsen; Vibeke Østergaard Thomsen; Morten Frydenberg; Bjørn Andersen Nexø; Jacob Sode; Ulla Vogel; Vibeke Andersen;
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年(卷),期 -1(9),6
年度 -1
页码 e98815
总页数 10
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1. Evaluating the role of the genetic variations of PTPN22, NFKB1, and FcGRIIIA genes in inflammatory bowel disease: a meta-analysis. [J] . Latiano A, Palmieri O, Valvano MR, Inflammatory bowel diseases . 2007,第10期

机译：评价PTPN22，NFKB1和FcGRIIIA基因的遗传变异在炎症性肠病中的作用：一项荟萃分析。
2. G2848A and T-1237C polymorphisms of the TLR9 gene and susceptibility to inflammatory bowel disease in patients from southern Brazil [J] . Valverde-VillegasJ.M., dosSantosB.P., MachadoM.B., Tissue antigens. . 2014,第3期

机译：TLR9基因的G2848A和T-1237C多态性与巴西南部患者的炎症性肠病易感性
3. Analysis of TLR4 and TLR2 polymorphisms in inflammatory bowel disease in a Guangxi Zhuang population. [J] . Lan Chen, Mei-Jiao Lin, Ling-Ling Zhan, World journal of gastroenterology : . 2012,第46期

机译：广西壮族人群炎症性肠病中TLR4和TLR2多态性的分析。
4. Significance of the wingless-type/beta-catenin signaling cascade for cancer risk in inflammatory bowel disease: Association of genetic polymorphism in human dishevelled 1 with dysplasia in ulcerative colitis. [D] . Uthoff, Sonja Martina Stefanie. 2004

机译：无翼型/β-连环蛋白信号传导级联对于炎症性肠病的癌症风险的意义：人类衣衫不整的1的遗传多态性与溃疡性结肠炎的不典型增生相关。
5. Association between TLR2 and TLR4 Gene Polymorphisms and the Susceptibility to Inflammatory Bowel Disease: A Meta-Analysis [O] . Yang Cheng, Yun Zhu, Xiuping Huang, -1

机译：TLR2和TLR4基因多态性与炎性肠病易感性的关联：荟萃分析
6. Polymorphisms in the Inflammatory Pathway Genes TLR2, TLR4, TLR9, LY96, NFKBIA, NFKB1, TNFA, TNFRSF1A, IL6R, IL10, IL23R, PTPN22, and PPARG Are Associated with Susceptibility of Inflammatory Bowel Disease in a Danish Cohort [O] . Bank, Steffen, Skytt Andersen, Paal, Burisch, Johan, 2014

机译：炎症队列基因TLR2，TLR4，TLR9，LY96，NFKBIA，NFKB1，TNFA，TNFRSF1A，IL6R，IL10，IL23R，PTPN22和PPARG的多态性与丹麦人群中炎症性肠病的易感性相关

Polymorphisms in the Inflammatory Pathway Genes TLR2 TLR4 TLR9 LY96 NFKBIA NFKB1 TNFA TNFRSF1A IL6R IL10 IL23R PTPN22 and PPARG Are Associated with Susceptibility of Inflammatory Bowel Disease in a Danish Cohort

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