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Isoniazid Pyrazinamide and Rifampicin Content Variation in Split Fixed-Dose Combination Tablets

机译：拆分固定剂量组合片剂中的异烟肼吡嗪酰胺和利福平含量变化

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摘要

SettingIn most developing countries, paediatric tuberculosis is treated with split tablets leading to potential inaccuracy in the dose delivery and drug exposure. There is no data on the quality of first-line drugs content in split fixed-dose combination tablets.

机译：设置在大多数发展中国家，小儿肺结核均采用分片治疗，从而导致剂量输送和药物暴露方面的潜在误差。没有关于固定剂量分装组合片剂中一线药物质量的数据。

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Thomas Pouplin; Pham Nguyen Phuong; Pham Van Toi; Julie Nguyen Pouplin; Jeremy Farrar;
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年(卷),期 -1(9),7
年度 -1
页码 e102047
总页数 7
原文格式 PDF
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专利

1. Optimization of a reversed-phase-high-performance thin-layer chromatography method for the separation of isoniazid, ethambutol, rifampicin and pyrazinamide in fixed-dose combination antituberculosis tablets [J] . Shewiyo D.H., Kaale E., Risha P.G., Journal of chromatography, A: Including electrophoresis and other separation methods . 2012,第Null期

机译：反相高效薄层色谱法用于固定剂量联合抗结核药中异烟肼，乙胺丁醇，利福平和吡嗪酰胺的分离
2. Bioequivalence assessment of rifampicin, isoniazid and pyrazinamide in a fixed dose combination of rifampicin, isoniazid, pyrazinamide and ethambutol vs. separate formulations. [J] . Agrawal S, Singh I, Kaur KJ, International journal of clinical pharmacology and therapeutics . 2002,第10期

机译：利福平，异烟肼，吡嗪酰胺和乙胺丁醇与单独制剂固定剂量组合中的利福平，异烟肼和吡嗪酰胺的生物等效性评估。
3. Treating More with Less: Effectiveness and Event Outcomes of Antituberculosis Fixed-dose Combination Drug versus Separate-drug Formulation (Ethambutol, Isoniazid, Rifampicin and Pyrazinamide) for Pulmonary Tuberculosis Patients in Real-world Clinical Practice [J] . Jacqueline Mui Lan Lai, Su Lan Yang, Richard Avoi Journal of Global Infectious Diseases . 2019,第1期

机译：事半功倍：实际临床实践中抗结核固定剂量联合药物与单独药物制剂（乙胺丁醇，异烟肼，利福平和吡嗪酰胺）对肺结核患者的有效性和事件结果
4. Studies on Combination of Non-ionic and Anionic Polymers in the Design of Controlled ReleaseFormulations of Rifampicin and Isoniazid [C] . Hiremath S. P., Saha R. N. Annual meeting exposition of the Controlled Release Society . 2005

机译：利福平和异烟肼控释制剂设计中非离子和阴离子聚合物的结合研究
5. Treatment of latent tuberculosis infection with isoniazid (INH) for nine months versus rifampin and pyrazinamide (RZ) for two months: A comparison of rate of liver injury in Baltimore City Chest Clinic during 1999--2001. [D] . Obiako, Emmanuel Chinasa. 2007

机译：异烟肼（INH）与利福平和吡嗪酰胺（RZ）两个月治疗潜伏性肺结核感染九个月：巴尔的摩市胸科诊所1999--2001年肝损伤率的比较。
6. Oral pyridoxine can substitute for intravenous pyridoxine in managing patients with severe poisoning with isoniazid and rifampicin fixed dose combination tablets: a case report [O] . M. D. S. A. Dilrukshi, C. A. P. Ratnayake, C. A. Gnanathasan 2017

机译：口服吡ido醇可以代替静脉注射吡ido醇治疗异烟肼和利福平固定剂量联合片剂严重中毒患者：一例
7. Isoniazid, pyrazinamide and rifampicin content variation in split fixed-dose combination tablets. [O] . Thomas Pouplin, Pham Nguyen Phuong, Pham Van Toi, 2014

机译：分裂固定剂量组合片剂中的异烟肼，吡嗪酰胺和利福平含量变化。

Isoniazid Pyrazinamide and Rifampicin Content Variation in Split Fixed-Dose Combination Tablets

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