Emergence of Streptococcus pneumoniae Serogroups 15 and 35 in Nasopharyngeal Cultures from Young Children with Acute Otitis Media

摘要

BackgroundSurveillance of children with acute otitis media (AOM) for nasopharyngeal colonization with Streptococcus pneumoniae before, during, and after the introduction of 7-valent pneumococcal conjugate vaccine (PCV7) indicated the near-complete elimination of PCV7 strains and the emergence of pneumococcal serotype 19A.