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Quantitative Signature of Coronary Steal in a Patient with Occluded Coronary Arteries Supported by Collateral Circulation Using Dynamic SPECT

机译:使用动态SPECT的侧支循环支持冠状动脉闭塞患者冠状动脉窃取的定量特征

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摘要

Coronary steal (CS) is a physiological process that induces absolute decrease in blood flow in collateralized myocardium compared to resting flow during coronary vasodilation due to redistribution of blood away from collateral-dependent myocardium. Although, CS has been well known for decades, there are very few noninvasive perfusion studies in humans that quantitatively predict the existence of CS. In this study, we show that the quantitative measurement of absolute value of regional myocardial blood flow (MBF) and coronary flow reserve (CFR) using dynamic single photon emitted computed tomography (SPECT) can help estimate the presence of CS in myocardium with obstructed coronary artery and collateral circulation.
机译:冠状动脉抢断(CS)是一种生理过程,与由于依赖于依赖侧支的心肌的血液再分配导致的冠状动脉舒张血管扩张期间的静息流相比,诱导了侧支的心肌的血流绝对减少。尽管CS已经众所周知了数十年,但在人类中很少有无创灌注研究定量地预测CS的存在。在这项研究中,我们表明使用动态单光子发射计算机断层扫描(SPECT)定量测量局部心肌血流(MBF)和冠状动脉血流储备量(CFR)的绝对值可以帮助估计冠状动脉梗阻心肌中CS的存在动脉和侧支循环。

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