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Trypanosoma cruzi I and IV Stocks from Brazilian Amazon Are Divergent in Terms of Biological and Medical Properties in Mice

机译：从亚马逊的生物学特性和医学特性来看巴西亚马逊的锥虫Trypanosoma cruzi I和IV存量存在差异

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BackgroundIn the Brazilian Amazon, clinical and epidemiological frameworks of Chagas disease are very dissimilar in relation to the endemic classical areas of transmission, possibly due to genetic and biological characteristics of the circulating Trypanosoma cruzi stocks. Twenty six T. cruzi stocks from Western Amazon Region attributed to the TcI and TcIV DTUs were comparatively studied in Swiss mice to test the hypothesis that T. cruzi clonal structure has a major impact on its biological and medical properties.

机译：背景技术在巴西亚马逊河地区，恰加斯病的临床和流行病学框架与地方病的经典传播区域非常不同，这可能是由于循环的锥虫锥虫种群的遗传和生物学特征所致。在瑞士小鼠中比较研究了来自西亚马逊地区的26种T.I和TcIV DTU的T. cruzi种群，以检验假说T. cruzi克隆结构对其生物学和医学特性具有重要影响的假说。

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期刊名称 PLoS Neglected Tropical Diseases
作者
Wuelton Marcelo Monteiro; Ana Paula Margioto Teston; Ana Paula Gruendling; Daniele dos Reis; Mônica Lúcia Gomes; Silvana Marques de Araújo; Maria Terezinha Bahia; Laylah Kelre Costa Magalhães; Jorge Augusto de Oliveira Guerra; Henrique Silveira; Max Jean de Ornelas Toledo; Maria das Graças Vale Barbosa;
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年(卷),期 2013(7),2
年度 2013
页码 e2069
总页数 9
原文格式 PDF
正文语种
中图分类寄生动物、寄生虫学;医学寄生虫学;
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1. Trypanosoma cruzi I and IV Stocks from Brazilian Amazon Are Divergent in Terms of Biological and Medical Properties in Mice [J] . Wuelton Marcelo Monteiro, Ana Paula Margioto Teston, Ana Paula Gruendling, PLOS Neglected Tropical Diseases . 2013,第2期

机译：就小鼠的生物学和医学特性而言，来自巴西亚马逊的Trypanosoma cruzi I和IV存量存在差异
2. Biological behavior of Trypanosoma cruzi stocks obtained from the state of Amazonas, Western Brazilian Amazon, in mice [J] . Max Jean De Ornelas Toledo Revista da Sociedade Brasileira de Medicina Tropical . 2012,第2期

机译：从巴西西部亚马逊河州亚马逊河州获得的锥虫锥虫的生物学行为
3. Biological behavior of Trypanosoma cruzi stocks obtained from the state of Amazonas, Western Brazilian Amazon, in mice [J] . Barbosa Maria das Gra?as Vale, Ferreira Luiz Carlos de Lima, Guerra Jorge Augusto de Oliveira, Sociedade Brasileira de Medicina Tropical. Revista . 2012,第2期

机译：从巴西西部亚马逊河州亚马逊河州获得的锥虫锥虫的生物学行为
4. Automated parasitaemia quantification in mice infected with Trypanosoma cruzi [C] . Carlos Augusto Centeno, Javier Alfredo Voos, Martin Alejandro Salamero, IEEE Congreso Bienal de Argentina . 2020

机译：用锥虫瘤Cruzi感染的小鼠中的自动寄生虫量化
5. Design, synthesis, and biological evaluation of molecules of medicinal interest: Inhibitors of mammalian and Trypanosoma cruzi protein farnesyltransferase and Trypanosoma cruzi lanosterol-14-alpha-demethylase. [D] . Lockman, Jeffrey William. 2003

机译：设计，合成和具有药用价值的分子的生物学评估：哺乳动物和克鲁斯锥虫蛋白法尼基转移酶和克鲁斯锥虫羊毛甾醇14-α-脱甲基酶的抑制剂。
6. Trypanosoma cruzi IV Causing Outbreaks of Acute Chagas Disease and Infections by Different Haplotypes in the Western Brazilian Amazonia [O] . Wuelton Marcelo Monteiro, Laylah Kelre Costa Magalhães, Amanda Regina Nichi de Sá, 2009

机译：克鲁格氏锥虫IV导致巴西巴西亚马逊河地区急性南美锥虫病暴发和不同单倍型感染
7. Trypanosoma cruzi I and IV stocks from Brazilian Amazon are divergent in terms of biological and medical properties in mice. [O] . Wuelton Marcelo Monteiro, Ana Paula Margioto Teston, Ana Paula Gruendling, 2013

机译：来自巴西亚马逊的Trypanosoma cruzi I和IV种群在小鼠的生物学和医学特性方面存在差异。
8. Experimental Chagas' Disease (Trypanosoma cruzi) in the Brazilian Squirrel Monkey (Saimiri sciureus): Hematology, Cardiology, Cellular and Humoral Immune Responses. (Reannouncement with New Availability Information). [R] . Pung, O. J., Hulsebos, L. H., Kuhn, R. E. 1988

机译：实验性恰加斯病（克氏锥虫）在巴西松鼠猴（saimiri sciureus）：血液学，心脏病学，细胞和体液免疫反应。（重新公布新的可用性信息）。

Trypanosoma cruzi I and IV Stocks from Brazilian Amazon Are Divergent in Terms of Biological and Medical Properties in Mice

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