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Optimizing ART Adherence: Update for HIV Treatment and Prevention

机译:优化抗病毒治疗的依从性:艾滋病治疗和预防的最新进展

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摘要

Optimal adherence to antiretroviral therapy (ART) is central to achieving viral suppression and positive health outcomes in HIV-infected individuals. Virally suppressed individuals can also reduce the risk of HIV transmission to uninfected partners. Hence, adherence to ART has become both an HIV treatment and an HIV prevention strategy. However, achieving optimal ART adherence can be challenging, especially over the long term. It is increasingly important for clinicians and researchers to be abreast of the most recent developments in the field as new biomedical approaches to treatment emerge, and as guidelines for the use of pre-exposure prophylaxis (PrEP) are disseminated to providers serving HIV affected populations. Several reviews have described numerous ART adherence interventions that have been developed and/or tested with the most recent review including literature up to 2012. To augment the literature, we present a review of ART adherence interventions from 2013 – present. We included peer-reviewed journals as well as abstracts from two key conferences.
机译:最佳地坚持抗逆转录病毒疗法(ART)对于在HIV感染者中实现病毒抑制和取得积极的健康成果至关重要。被病毒抑制的个体还可以降低HIV传播给未感染伴侣的风险。因此,坚持抗病毒治疗已成为一种艾滋病治疗和一项艾滋病预防策略。但是,实现最佳的ART依从性可能是一项挑战,特别是从长期来看。随着新的生物医学治疗方法的出现以及向使用HIV的人群提供暴露前预防(PrEP)指南的传播,临床医生和研究人员必须紧跟该领域的最新发展。几篇综述描述了许多ART依从性干预措施,这些干预措施已用最新的综述(包括截至2012年的文献)进行了开发和/或测试。为充实文献,我们对2013年至今的ART依从性干预措施进行了综述。我们收录了同行评审期刊以及两次重要会议的摘要。

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