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The Ovarian Cancer Chemokine Landscape is Conducive to Homing of Vaccine-primed and CD3/CD28 Costimulated T cells Prepared for Adoptive Therapy

机译：卵巢癌趋化因子的格局有利于归巢疫苗准备和CD3 / CD28共刺激的T细胞为过继疗法的准备。

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PurposeChemokines are implicated in T cell trafficking. We mapped the chemokine landscape in advanced stage ovarian cancer and characterized the expression of cognate receptors in autologous DC-vaccine primed T cells in the context of cell-based immunotherapy.

机译：目的趋化因子与T细胞运输有关。我们绘制了晚期卵巢癌的趋化因子分布图，并在基于细胞的免疫疗法中表征了自体DC疫苗致敏T细胞中同源受体的表达。

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作者
Emese Zsiros; Priyanka Duttagupta; Denarda Dangaj; Hongzhe Li; Renee Frank; Thomas Garrabrant; Ian S. Hagemann; Bruce L. Levine; Carl H. June; Lin Zhang; Ena Wang; Francesco M. Marincola; Davide Bedognetti; Daniel J. Powell Jr.; Janos Tanyi; Michael D. Feldman; Lana E. Kandalaft; George Coukos;
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年(卷),期 -1(21),12
年度 -1
页码 2840–2850
总页数 22
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专利

1. The Ovarian Cancer Chemokine Landscape Is Conducive to Homing of Vaccine-Primed and CD3/CD28-Costimulated T Cells Prepared for Adoptive Therapy [J] . Zsiros Emese, Duttagupta Priyanka, Dangaj Denarda, Clinical cancer research: an official journal of the American Association for Cancer Research . 2015 ,第12期

机译：卵巢癌趋化因子的格局有助于归巢疫苗和CD3 / CD28刺激的T细胞为过继治疗准备。
2. Immune modulation in cancer patients after adoptive transfer of anti-CD3/anti-CD28-costimulated T cells-phase I clinical trial. [J] . Lum LG, LeFever AV, Treisman JS, Journal of immunotherapy . 2001 ,第5期

机译：过继转移抗CD3 /抗CD28共同刺激的T细胞的I期临床试验对癌症患者的免疫调节
3. Immune Modulation in Cancer Patients After Adoptive Transfer of Anti-CD3/Anti-CD28-Costimulated T Cells-Phase I Clinical Trial. [J] . Lum LG, Treisman JS, Hanson-Jr JP Journal of immunotherapy . 2001 ,第5期

机译：在抗CD3 /抗CD28协同刺激的T细胞过继转移的I期临床试验中对癌症患者的免疫调节
4. Vaccine-Primed Lymph Node Cells In the Adoptive Immunotherapy of Cancer: Presence of Host Immune Suppression Induced by Established Cancer [C] . Shuang Wei, Andrew B. Shreiner, Alfred E. Chang International Symposium on Cancer Metastasis and the Lymphovascular system: Basis for Rational Therapy . 2009

机译：癌症的疫苗引发淋巴结细胞：癌症的存在免疫抑制因成立癌症诱导
5. Fatty Acid-like Pt(IV) Prodrugs Harnessing CD36 to Target Chemoresistant Ovarian Cancer Cells [D] . Qiu, Zihan. 2019

机译：利用CD36靶向化学抗性卵巢癌细胞的脂肪酸样Pt（IV）前药
6. Combination Immunotherapy after ASCT for Multiple Myeloma Using MAGE-A3/Poly-ICLC Immunizations Followed by Adoptive Transfer of Vaccine-Primed and Costimulated Autologous T Cells [O] . Aaron P. Rapoport, Nicole A. Aqui, Edward A Stadtmauer, -1

机译：使用MAGE-A3 / Poly-ICLC免疫接种对多发性骨髓瘤进行ASCT后的联合免疫治疗然后转移以疫苗为基础的和共同刺激的自体T细胞的过继转移
7. The Ovarian Cancer Chemokine Landscape Is Conducive to Homing of Vaccine-Primed and CD3/CD28-Costimulated T Cells Prepared for Adoptive Therapy. [O] . Zsiros, E., Duttagupta, P., Dangaj, D., 2015

机译：卵巢癌趋化因子态势有利于为过继治疗准备的以疫苗为主的和CD3 / CD28协同刺激的T细胞的归巢。
8. Adoptive Immunotherapy for Epithelial Ovarian Cancer Using T-cells Simultaneously Targeted to Tumor and Tumor-Associated Macrophages. [R] . Maher, J., Ghaem-Maghami, S. 2013

机译：上皮性卵巢癌的过继免疫治疗使用T细胞同时针对肿瘤和肿瘤相关的巨噬细胞。

The Ovarian Cancer Chemokine Landscape is Conducive to Homing of Vaccine-primed and CD3/CD28 Costimulated T cells Prepared for Adoptive Therapy

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