Washing stored red blood cells in an albumin solution improves their morphological and hemorheological properties

摘要

BACKGROUNDProlonged storage of red blood cells leads to storage lesions, which may impair clinical outcomes after transfusion. A hallmark of storage lesions is progressive echinocytic shape transformation, which can be partially reversed by washing in albumin solutions. Here we have investigated the impact of this shape recovery on biorheological parameters.