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IL-11 Attenuates Liver Ischemia/Reperfusion Injury (IRI) through STAT3 Signaling Pathway in Mice

机译：IL-11通过STAT3信号通路减轻小鼠肝脏缺血/再灌注损伤（IRI）

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BackgroundThe protective role of IL-11, an IL-6 family cytokine, has been implicated in ischemia/reperfusion injury (IRI) in the heart and kidney, but its role has not been elucidated in liver IRI. This study was designed to evaluate the effects of IL-11 and its mechanism of action on liver IRI in a mouse model.

机译：背景技术IL-11（一种IL-6家族细胞因子）的保护作用与心脏和肾脏的缺血/再灌注损伤（IRI）有关，但在肝IRI中尚未阐明其作用。本研究旨在评估小鼠模型中IL-11的作用及其对肝脏IRI的作用机制。

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期刊名称 other
作者
Miao Zhu; Bo Lu; Qinhong Cao; Zhenfeng Wu; Zhe Xu; Weisu Li; Xuequan Yao; Fukun Liu;
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年(卷),期 -1(10),5
年度 -1
页码 e0126296
总页数 15
原文格式 PDF
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专利

1. Calycosin-7-O-beta-d-glucoside attenuates myocardial ischemia-reperfusion injury by activating JAK2/STAT3 signaling pathway via the regulation of IL-10 secretion in mice [J] . Liu Yujie, Che Guoying, Di Zhixin, Molecular and Cellular Biochemistry: An International Journal for Chemical Biology . 2020 ,第1a2期

机译：通过在小鼠中调节IL-10分泌物，通过激活JAK2 / Stat3信号通路来衰减心肌缺血再灌注损伤的心肌缺血性损伤
2. Short-term starvation attenuates liver ischemia-reperfusion injury (IRI) by Sirt1-autophagy signaling in mice [J] . Jianjie Qin, Junjin Zhou, Xinzheng Dai, American Journal of Translational Research . 2016 ,第8期

机译：短期饥饿通过Sirt1自噬信号在小鼠中减轻肝脏缺血再灌注损伤（IRI）
3. Canonical Notch Pathway Protects Hepatocytes from Ischemia/Reperfusion Injury in Mice by Repressing Reactive Oxygen Species Production Through JAK2/STAT3 Signaling [J] . Heng Chao Yu, Hong Yan Qin, Fei He, Hepatology: Official Journal of the American Association for the Study of Liver Diseases . 2011 ,第3期

机译：典型的缺口途径通过抑制通过JAK2 / STAT3信号产生的活性氧来保护小鼠肝细胞免受缺血/再灌注损伤。
4. Protective Role of N-Acetyl-L-Tryptophan against Hepatic Ischemia-Reperfusion Injury by the TLR4/NF-KB Signaling pathway [C] . Jianxin Wang, Shuna Yu, Huiting Li, International Conference on Frontiers of Biological Sciences and Engineering . 2019

机译：N-乙酰-1-色氨酸对TLR4 / NF-KB信号通路对肝缺血再灌注损伤的保护作用
5. Normothermic ex-situ Liver Perfusion and PPAR-γ Activation as Strategies to Reduce Liver Ischemia Reperfusion Injury [D] . Linares Cervantes, Iván de Jesús. 2019

机译：常温前肝灌注和PPAR-γ活化作为降低肝脏缺血再灌注损伤的策略
6. Short-term starvation attenuates liver ischemia-reperfusion injury (IRI) by Sirt1-autophagy signaling in mice [O] . Jianjie Qin, Junjin Zhou, Xinzheng Dai, 2016

机译：短期饥饿通过Sirt1自噬信号在小鼠中减轻肝脏缺血再灌注损伤（IRI）
7. IL-11 Attenuates Liver Ischemia/Reperfusion Injury (IRI) through STAT3 Signaling Pathway in Mice. [O] . Miao Zhu, Bo Lu, Qinhong Cao, 2015

机译：IL-11通过小鼠sTaT3信号通路减轻肝脏缺血/再灌注损伤（IRI）。

IL-11 Attenuates Liver Ischemia/Reperfusion Injury (IRI) through STAT3 Signaling Pathway in Mice

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