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Intolerance of uncertainty as a mediator of reductions in worry in a cognitive behavioral treatment program for generalized anxiety disorder

机译:在广泛性焦虑症的认知行为治疗计划中不确定性不能作为减轻忧虑的中介

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摘要

Growing evidence suggests that intolerance of uncertainty (IU) is a cognitive vulnerability that is a central feature across diverse anxiety disorders, including generalized anxiety disorder (GAD). Although cognitive behavioral therapy (CBT) has been shown to reduce IU, it remains to be established whether or not reductions in IU mediate reductions in worry. This study examined the process of change in IU and worry in a sample of 28 individuals with GAD who completed CBT. Changes in IU and worry, assessed bi-weekly during treatment, were analyzed using multilevel mediation models. Results revealed that change in IU mediated change in worry (ab = -0.20; 95% CI [-.35, -.09]), but change in worry did not mediate change in IU (ab = -0.16; 95% CI [-.06, .12]). Findings indicated that reductions in IU accounted for 59% of the reductions in worry observed over the course of treatment, suggesting that changes in IU are not simply concomitants of changes in worry. Findings support the idea that IU is a critical construct underlying GAD.
机译:越来越多的证据表明,不确定性的不宽容(IU)是一种认知脆弱性,是包括广泛性焦虑症(GAD)在内的各种焦虑症的主要特征。尽管认知行为疗法(CBT)已显示可以减少IU,但是否减少IU可以介导减轻忧虑仍有待确定。这项研究从28位完成CBT的GAD个体中检查了IU变化和焦虑的过程。使用多级调解模型分析治疗期间每两周评估一次的IU和焦虑的变化。结果显示,IU的变化介导了忧虑的变化(ab = -0.20; 95%CI [-.35,-。09]),但忧虑的变化并未介导IU的变化(ab = -0.16; 95%CI [ -.06,.12])。研究结果表明,在治疗过程中,IU减少量占忧虑减轻量的59%,这表明IU的改变不仅仅是忧虑改变的伴随物。研究结果支持IU是GAD基础的关键构想。

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