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Uncontrolled blood pressure and risks of sleep apnea among Blacks: Findings from the Metabolic Syndrome Outcome (MetSO) study

机译:黑人中血压不受控制和睡眠呼吸暂停的风险:代谢综合征结果(MetSO)研究的发现

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摘要

Uncontrolled blood pressure (BP) is linked to increased risk of obstructive sleep apnea (OSA). However, few studies have assessed the impact of this relationship among blacks with metabolic syndrome. Data for this study were collected from 1,035 blacks (mean age = 62±13 years) enrolled in the Metabolic Syndrome Outcome (MetSO) study. Patients with a score ≥6 on the Apnea Risk Evaluation System (ARES™) were considered at risk for OSA. Of the sample, 77.1% were low-to-high OSA risk and 92.3% were hypertensive, of which 16.8% had uncontrolled BP levels. Analysis also showed 60.4% were diabetic, 8.9% had a stroke history, 74.3% had dyslipidemia, 69.8% were obese and 30.9% had a history of heart disease. Logistic regression analyses were employed to investigate associations between uncontrolled BP and OSA risk, while adjusting for known covariates. Findings showed that uncontrolled BP independently increased the odds of OSA risk twofold (OR = 2.02, 95% CI = 1.18–3.48, p < 0.05). Our findings show that uncontrolled BP was associated with a twofold greater risk of OSA among blacks, suggesting that those with metabolic syndrome and who have uncontrolled BP should be screened for the presence of OSA.
机译:血压失控与阻塞性睡眠呼吸暂停(OSA)风险增加有关。但是,很少有研究评估黑人与代谢综合征之间这种关系的影响。这项研究的数据来自参加代谢综合征结果(MetSO)研究的1,035名黑人(平均年龄= 62±13岁)。在呼吸暂停风险评估系统(ARES™)上得分≥6的患者被认为有OSA风险。在样本中,低至高OSA风险为77.1%,高血压为92.3%,其中16.8%的血压水平不受控制。分析还显示,糖尿病的患病率为60.4%,有中风史的为8.9%,血脂异常的为74.3%,肥胖的为69.8%,有心脏病的史为30.9%。使用逻辑回归分析来调查不受控制的BP与OSA风险之间的关联,同时调整已知的协变量。研究结果表明,不受控制的BP独立增加了OSA风险的几率(OR = 2.02,95%CI = 1.18–3.48,p <0.05)。我们的研究结果表明,黑人血压不受控制与OSA风险高两倍有关,这表明患有代谢综合征和血压不受控制的黑人应进行OSA筛查。

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