Control of Mesh Size and Modulus by Kinetically Dependent Cross-linking in Hydrogels

摘要

>Kinetically controlled cross-linking processes produce mechanically distinguishable hydrogels using identical precursor chemistry. The oxime ligation demonstrates tunable reaction kinetics with pH and buffer strength, which induces changes in the structural features of hydrogels and determines their mechanical properties. Small-angle neutron scattering and swelling studies provide insight into how structural properties correlate with mechanical properties for this hydrogel system.