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Serum Autotaxin/ENPP2 Correlates with Insulin Resistance in Older Humans with Obesity

机译：老年肥胖者血清自分泌运动素/ ENPP2与胰岛素抵抗相关

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摘要

ObjectiveAutotaxin (ATX) is an adipocyte-derived lysophospholipase D that generates the lipid signaling molecule lysophosphatidic acid (LPA). The ATX/LPA pathway in adipose tissue has recently been implicated in obesity and insulin resistance in animal models, but the role of circulating ATX in humans remains unclear. The aim of the present study was to determine the relationship between serum ATX and insulin resistance.

机译：ObjectiveAutotaxin（ATX）是源自脂肪细胞的溶血磷脂酶D，可产生脂质信号分子溶血磷脂酸（LPA）。在动物模型中，脂肪组织中的ATX / LPA途径最近与肥胖和胰岛素抵抗有关，但循环ATX在人类中的作用仍不清楚。本研究的目的是确定血清ATX与胰岛素抵抗之间的关系。

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期刊名称 other
作者
Valerie L. Reeves; Joy S. Trybula; Rachel C. Wills; Bret H. Goodpaster; John J. Dubé; Petra C. Kienesberger; Erin E. Kershaw;
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年(卷),期 -1(23),12
年度 -1
页码 2371–2376
总页数 15
原文格式 PDF
正文语种
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关键词
Autotaxin adipokines lysophosphatidic acid obesity insulin resistance metabolic syndrome;

机译：自分泌运动素;脂肪因子;溶血磷脂酸;肥胖;胰岛素抵抗;代谢综合征;

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专利

1. Serum Autotaxin/ENPP2 Correlates with Insulin Resistance in Older Humans with Obesity [J] . Reeves Valerie L., Trybula Joy S., Wills Rachel C., Obesity . 2015,第12期

机译：老年肥胖者的血清自分泌运动素/ ENPP2与胰岛素抵抗相关
2. Serum Myostatin is Upregulated in Obesity and Correlates with Insulin Resistance in Humans [J] . Amor Melina, Itariu Bianca K., Moreno-Viedma Veronica, Experimental and clinical endocrinology and diabetes: Official journal, German Society of Endocrinology [and] German Diabetes Association . 2019,第8期

机译：血清myostatin以肥胖症上调，与人类胰岛素抵抗相关
3. Serum RBP4 positively correlates with triglyceride level but not with BMI, fat mass and insulin resistance in healthy obese and non-obese individuals [J] . Korek Emilia, Gibas-Dorna Magdalena, Checinska-Maciejewska Zuzanna, Biomarkers . 2018,第1a8期

机译：健康肥胖者和非肥胖者的血清RBP4与甘油三酯水平呈正相关，与BMI，脂肪量和胰岛素抵抗无关
4. FT–IR Saliva Profiling in Patients with Obesity and Obesity–Related Insulin Resistance [C] . S.A. Pullano, M. Greco, M.G. Bianco, IEEE International Symposium on Medical Measurements and Applications . 2019

机译：肥胖患者及与肥胖相关的胰岛素抵抗患者的FT-IR唾液分析
5. Grape polyphenols attenuate inflammation and insulin resistance in human adipocytes and obese mice. [D] . Chuang, Chia-Chi. 2012

机译：葡萄多酚可减轻人脂肪细胞和肥胖小鼠的炎症和胰岛素抵抗。
6. Serum C1q/TNF-related protein-3 (CTRP3) levels are decreased in obesity and hypertension and are negatively correlated with parameters of insulin resistance [O] . Wuquan Deng, Changyan Li, Yuping Zhang, 2015

机译：肥胖和高血压患者血清C1q / TNF相关蛋白3（CTRP3）水平降低并且与胰岛素抵抗参数负相关
7. Serum Autotaxin/ENPP2 correlates with insulin resistance in older humans with obesity [O] . Valerie L. Reeves, Joy S. Trybula, Rachel C. Wills, 2015

机译：血清Autotaxin / Enpp2与肥胖症的旧人类的胰岛素抵抗相关

Serum Autotaxin/ENPP2 Correlates with Insulin Resistance in Older Humans with Obesity

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