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Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study

机译：与双相情感障碍锂治疗反应相关的遗传变异：全基因组关联研究

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BackgroundLithium remains a first-line treatment in bipolar disorder, but individual response is variable. Previous studies have suggested that lithium response is a heritable trait. However, no genetic markers have been reproducibly identified.

机译：背景锂仍是双相情感障碍的一线治疗方法，但个人反应不定。先前的研究表明锂反应是一种遗传性状。但是，没有可重复地鉴定出遗传标记。

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1. Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study [J] . Hou Liping, Heilbronner Urs, Degenhardt Franziska, The Lancet . 2016,第10023期

机译：与双相情感障碍锂治疗反应相关的遗传变异：全基因组关联研究
2. Association of polygenic score for schizophrenia and HLA antigen and inflammation genes with response to lithium in bipolar affective disorder: A genome-wide association study [J] . International Consortium on Lithium Genetics (ConLi+Gen) JAMA psychiatry . 2018,第1期

机译：精神分裂症和HLA抗原和炎症基因的多基因分数与双极情感障碍锂的抗炎基因的关系：基因组 - 宽协会研究
3. Evidence for association of an ACCN1 gene variant with response to lithium treatment in Sardinian patients with bipolar disorder. [J] . Squassina A, Manchia M, Borg J, Pharmacogenomics . 2011,第11期

机译：撒丁岛双相情感障碍患者中ACCN1基因变异与锂治疗反应相关的证据。
4. Genome-wide association study identified genetic variants associated with severity of COPD in Korean participants [C] . Geumkyung Nah, Jiwon Kim, Eun-A Choi, IEEE International Conference on Bioinformatics and Biomedicine . 2020

机译：基因组关联研究确定了与韩国参与者的COPD严重程度相关的遗传变异
5. Bayesian Hierarchical Models for Multi-Variant and Multi-Trait Genome-Wide Association Studies [D] . ?Yang, Yi 2020

机译：多变体和多特质基因组协会研究的贝叶斯级分层模型
6. Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report [O] . Mirko Manchia, Mazda Adli, Nirmala Akula, -1

机译：双相情感障碍对锂维持治疗的反应评估：锂遗传学联盟（ConLiGen）报告
7. Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study [O] . Hou, Liping, Heilbronner, Urs, Degenhardt, Franziska, 2016

机译：与双相情感障碍锂治疗反应相关的遗传变异：全基因组关联研究

Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study

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