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Targeted Sequencing of an Epidemiologically Low Risk patient defines Fibroblast Growth Factor Family Aberrations as a putative driver of Head and Neck Squamous Cell Carcinoma

机译：流行病学低风险患者的靶向测序将成纤维细胞生长因子家族畸变定义为头颈部鳞状细胞癌的推定驱动力

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BackgroundTargeted sequencing of epidemiologically low risk (ELR) HNSCC patients could help identify novel drivers or lost suppressors leading to precision medicine protocols and improved survival rates.

机译：背景流行病学低风险（ELR）HNSCC患者的靶向测序可以帮助确定新型驱动因素或抑制因子，从而导致精确的医学方案并提高生存率。

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期刊名称 other
作者
Brittny N. Tillman; Megan Yanik; Andrew C. Birkeland; Chia-Jen Liu; Daniel H. Hovelson; Andi K. Cani; Nallasivam Palanisamy; Shannon Carskadon; Thomas E. Carey; Carol R. Bradford; Scott A. Tomlins; Jonathan B. McHugh; Matthew E. Spector; J. Chad Brenner;
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年(卷),期 -1(38),Suppl 1
年度 -1
页码 E1646–E1652
总页数 15
原文格式 PDF
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关键词
HNSCC FGF FGFR Amplification Mutant;

机译：HNSCC;FGF;FGFR;扩增;突变;

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专利

1. 526 Cancer-associated fibroblasts desensitizes head and neck squamous cell carcinoma cells to epidermal growth factor receptor-targeted therapy [J] . A.Johansson, A.Ansell, A.?stman, European Journal of Cancer Supplements . 2010,第5期

机译：526癌症相关的成纤维细胞使头颈部鳞状细胞癌细胞对表皮生长因子受体靶向治疗不敏感
2. Epidemiological characteristics of a Spanish cohort of patients diagnosed with squamous cell carcinoma of head and neck: distribution of risk factors by tumor location [J] . Seijas-Tamayo R., Fernandez-Mateos J., Adansa Klain J. C., Clinical & translational oncology : . 2016,第11期

机译：西班牙队列中诊断为头颈部鳞状细胞癌的患者的流行病学特征：肿瘤部位的危险因素分布
3. Fibroblast Growth Factor Receptor Family Members as Prognostic Biomarkers in Head and Neck Squamous Cell Carcinoma: A Systematic Review [J] . Ipenburg Norbertus A., Koole Koos, Liem K. Seng, Targeted oncology . 2016,第1期

机译：成纤维细胞生长因子受体家族成员作为头颈部鳞状细胞癌的预后生物标志物：系统评价。
4. CCND1 as a Predictive Biomarker of Neoadjuvant Chemotherapy in Patients with Locally Advanced Head and Neck Squamous Cell Carcinoma [C] . Zhien Feng, Lizhen Wang, Bingshun Wang, Academic Committee Conference of Shanghai key lab of stomatology . 2011

机译：CCND1作为局部晚期头颈部鳞状细胞癌患者新辅助化疗的预测生物标志物
5. The prognostic potential of the epidermal growth factor receptor and nuclear factor kappa B pathways and associated therapeutic strategies in patients with squamous cell carcinoma of the head and neck. [D] . Wirth, Pamela Susan. 2010

机译：表皮生长因子受体和核因子κB通路对头颈部鳞状细胞癌患者的预后潜力及相关治疗策略。
6. Fibroblast Growth Factor Receptor Family Members as Prognostic Biomarkers in Head and Neck Squamous Cell Carcinoma: A Systematic Review [O] . Norbertus A. Ipenburg, Koos Koole, K. Seng Liem, -1

机译：成纤维细胞生长因子受体家族成员作为头颈部鳞状细胞癌的预后生物标志物：系统评价。
7. Fibroblast growth factor family aberrations as a putative driver of head and neck squamous cell carcinoma in an epidemiologically low-risk patient as defined by targeted sequencing [O] . Brittny N. Tillman, Megan Yanik, Andrew C. Birkeland, 2016

机译：成纤维细胞生长因子家族像畸变作为由靶测序定义的流行病学低风险患者的头部和颈部鳞状细胞癌的推定驾驶员

Targeted Sequencing of an Epidemiologically Low Risk patient defines Fibroblast Growth Factor Family Aberrations as a putative driver of Head and Neck Squamous Cell Carcinoma

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