Prediction of Imminent Severe Deterioration of Children With Parallel Circulations Using Real-Time Processing of Physiologic Data

摘要

ObjectivesSudden death is common in patients with hypoplastic left heart syndrome and comparable lesions with parallel systemic and pulmonary circulation from a common ventricular chamber. It is hypothesized that unforeseen acute deterioration is preceded by subtle changes in physiologic dynamics prior to overt clinical extremis. Our objective is to develop a computer algorithm to automatically recognize precursors to deterioration in real-time, providing an early warning to care staff.