Wheelchair use and Lipophilic Statin Medications May Influence Bone Loss in Chronic Spinal Cord Injury: Findings from the FRASCI-bone loss Study

摘要

PurposeSpinal cord injury (SCI) increases the risk of osteoporosis and low-impact fractures, particularly at the knee. However, during the chronic phase of SCI, the natural history and factors associated with longitudinal change in bone density remain poorly characterized. In this study we prospectively assessed factors associated with change in bone density over a mean of 21 months in 152 men and women with chronic SCI.