Obstructive sleep apnea during REM sleep: Clinical relevance and therapeutic implications

摘要

Purpose of reviewObstructive sleep apnea (OSA) is a highly prevalent condition that has been associated with cardiovascular morbidity and mortality, impaired glucose metabolism and daytime functional impairment. Compared with non-rapid eye movement (NREM) sleep, rapid eye movement (REM) sleep is associated with higher sympathetic activity and cardiovascular instability in healthy individuals and more so in patients with OSA.