The Use of Non-Contrast Quantitative MRI to Detect Gadolinium-Enhancing Multiple Sclerosis Brain Lesions: A Systematic Review and Meta-Analysis

摘要

BackgroundConcerns have arisen about the long-term health effects of repeated gadolinium injections in multiple sclerosis (MS) patients and the incomplete characterization of MS lesion pathophysiology that results from relying on enhancement characteristics alone.