Non-Gaussian Diffusion Imaging with a Fractional Order Calculus Model to Predict Response of Gastrointestinal Stromal Tumor to Second-line Sunitinib Therapy

摘要

PurposeTo demonstrate the clinical value of a non-Gaussian diffusion model using fractional order calculus (FROC) for early prediction of the response of gastrointestinal stromal tumor (GIST) to second-line sunitinib targeted therapy.