BLUE VERSUS GRAY: POTENTIAL HEALTH BENEFITS OF BLUEBERRIES FOR SUCCESSFUL AGING

摘要

Emerging evidence from both preclinical and clinical studies have generated evidence of the potential health benefits of consuming blueberries (BBs). This fruit contains among the highest levels of polyphenols identified that provide highly effective antioxidant protection in addition to activating a wide range of other stress signaling pathways directly impacting health. The challenge now is to identify mechanisms through which BBs mediate their health benefits. Based on a wide range of preclinical and clinical studies, D Ingram (LSU, USA) will chair this symposium to review progress in assessing the health effects of BBs to promote successful aging. A Rodriguez-Mateos (U. Duesseldorf, GERMANY) will review studies examining the cardiovascular effects of BBs. CM Williams (U Reading, UK) will examine the cognitive effects of BB consumption in children and adults. B Shukitt-Hale (USDA/Tufts U, USA) will present data examining the effects of BB on motor and cognitive performance and brain inflammation in older adults. Y Desjardins (Laval U, CANADA) will present findings highlighting effects of BB consumption on the microbiome and its impact upon various health parameters. D Ingram will conclude with a talk focused on the concept of “hormesis.” Specifically, he will present data showing that berry fruits provide long-term protection against oxidative stress because they initially generate an essential mild oxidative stress.