Prediction of treatment outcomes to exercise in patients with non-remitted Major Depressive Disorder

摘要

BackgroundOnly one-third of patients with Major Depressive Disorder (MDD) achieve remission with initial treatment. Consequently, current clinical practice relies on a “trial-and-error” approach to identifying an effective treatment for each patient. The purpose of this report was to determine whether we could identify a set of clinical and biological parameters with potential clinical utility for prescription of exercise for treatment of MDD in a secondary analysis of the Treatment with Exercise Augmentation in Depression (TREAD) trial.