Decreased Spontaneous Activity and Altered Evoked Nociceptive Response of Rat Thalamic Submedius Neurons to Lumbar Vertebra Thrust

摘要

ObjectivesThe thalamus is a central structure important to modulating and processing all mechanoreceptor input destined for the cortex. A large number of diverse mechanoreceptor endings are stimulated when a high velocity low amplitude thrust is delivered to the lumbar spine during spinal manipulation. The objective of this study was to determine if a lumbar thrust alters spontaneous and/or evoked nociceptive activity in medial thalamic submedius (Sm) neurons.