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Polymorphisms in manganese transporters show developmental stage and sex specific associations with manganese concentrations in primary teeth

机译：锰转运蛋白的多态性显示发育阶段和性别特异性与乳牙中锰浓度的关联

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Background:Manganese (Mn) is an essential metal that can become neurotoxic at elevated levels with negative consequences on neurodevelopment. We have evaluated the influence of single nucleotide polymorphisms (SNPs) in Mn transporter genes SLC30A10 and SLC39A8 on Mn concentrations in dentine, a validated biomarker that reflects Mn tissue concentrations early in life.

机译：背景：锰（Mn）是一种必需金属，在高水平时会产生神经毒性，对神经发育产生负面影响。我们已经评估了锰转运蛋白基因SLC30A10和SLC39A8中单核苷酸多态性（SNPs）对牙本质中Mn浓度的影响，这是一种经过验证的生物标记物，可以反映生命早期Mn的浓度。

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期刊名称 other
作者
Karin Wahlberg; Manish Arora; Austen Curtin; Paul Curtin; Robert O. Wright; Donald R. Smith; Roberto G. Lucchini; Karin Broberg; Christine Austin;
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年(卷),期 -1(64),-1
年度 -1
页码 103–109
总页数 16
原文格式 PDF
正文语种
中图分类
关键词
Manganese homeostasis Manganese neurotoxicity Manganese transporter genetics Teeth biomarkers SLC30A10 SLC39A8;

机译：锰稳态;锰神经毒性;锰转运蛋白遗传学;牙齿生物标志物;SLC30A10;SLC39A8;

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专利

1. Polymorphisms in manganese transporters show developmental stage and sex specific associations with manganese concentrations in primary teeth [J] . Wahlberg Karin, Arora Manish, Curtin Austen, Neurotoxicology . 2018,第期

机译：锰转运蛋白的多态性显示出原发性牙齿中锰浓度的发育阶段和性别特异性关联
2. Manganese in teeth and neurobehavior: Sex-specific windows of susceptibility [J] . Bauer Julia Anglen, Henn Birgit Claus, Austin Christine, Environment international . 2017,第nova期

机译：牙齿和神经行为中的锰：易感染性别的特定窗口
3. DETERMINATION OF MANGANESE IN COW BLOOD USING THE FLAMELESS ATOMIC ABSORPTION SPECTROPHOTOMETRY. II. POPULATION INVESTIGATIONS INTO THE VARIABILITY OF MANGANESE CONCENTRATIONS IN THE SERUM AND BLOOD OF COWS IN VARIOUS PRODUCTION STAGES [J] . MAREK GEHRKE, ANDRZEJ LACHOWSKI Bulletin of the Veterinary Institute in Pulawy . 1997,第2期

机译：火焰原子吸收分光光度法测定牛血中的锰二。各种生产阶段牛血清和血液中锰浓度变化的人口调查
4. Associations between Personal Exposure to Airborne Manganese and Biomarkers of Internal Manganese Dose among Children in Northern Italy [C] . Hsiao-Hsien Leon Hsu, Robert O. Wright, Brent A. Coull, Annual conference of the International Society of Exposure Science . 2014

机译：意大利北部儿童中个人暴露于空气中的锰与内部锰剂量生物标志物之间的关联
5. Sibling-based association study of dopamine transporter, serotonin transporter, and dopamine-4 receptor polymorphisms and disordered eating behavior in young adults. [D] . Sobik, Laura Elizabeth. 2007

机译：基于兄弟姐妹的多巴胺转运蛋白，血清素转运蛋白和多巴胺-4受体多态性与年轻人饮食行为紊乱的关联研究。
6. Polymorphisms in Manganese Transporters SLC30A10 and SLC39A8 Are Associated With Childrens Neurodevelopment by Influencing Manganese Homeostasis [O] . Karin E. Wahlberg, Stefano Guazzetti, Daniela Pineda, 2018

机译：锰转运蛋白SLC30A10和SLC39A8的多态性通过影响锰稳态而与儿童的神经发育相关。
7. Polymorphisms in manganese transporters show developmental stage and sex specific associations with manganese concentrations in primary teeth [O] . Wahlberg, Karin, Arora, Manish, Curtin, Austen, 2017

机译：锰转运蛋白的多态性显示出发育阶段和性别特异性与主要牙齿中锰浓度的关联
8. Manganese Concentrations in Air Resulting from the Possible Use of Manganese Compounds as a Diesel Fuel Additive and Health Effect Aspects of Manganese [R] . Kuhler, M. , Kraft, J. , Hertel, R. F. 1984

机译：可能使用锰化合物作为柴油添加剂和锰的健康影响因素导致的空气中的锰浓度

Polymorphisms in manganese transporters show developmental stage and sex specific associations with manganese concentrations in primary teeth

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