Minocycline Effects on Intracerebral Hemorrhage-Induced Iron Overload in Aged Rats: Brain Iron Quantification with MRI

摘要

Background and PurposeBrain iron overload is a key factor causing brain injury after intracerebral hemorrhage (ICH). This study quantified brain iron levels after ICH with magnetic resonance imaging (MRI) R2* mapping. The effect of minocycline on iron overload and ICH-induced brain injury in aged rats was also determined.