Depression and risk of Alzheimer’s dementia: A longitudinal analysis to determine predictors of increased risk among older adults with depression.

摘要

Objective:Older adults with depression are at increased risk of Alzheimer’s dementia (AD) but predictors of increased risk remain incompletely understood. We aim to identify characteristics of older adults with depression most at most risk of progressing to AD. Identification of high-risk subgroups could facilitate future interventional strategies to reduce risk of AD in older adults with depression.