Placebo Effects across Self-Report Clinician-Rating and Objective Performance Tasks among Women with PTSD

摘要

Purpose/BackgroundFor a drug to acquire Food and Drug Administration approval, it must significantly outperform placebo treatment. In recent years, the placebo effect seems to be increasing in neuropsychiatric conditions. Here we examine placebo effects across self-reported, clinically rated, and performance based data from a trial using a corticotropin releasing horomone receptor type 1 (CRHR1) antagonist for treatment of post-traumatic stress disorder (PTSD).