Influenza vaccine failure: Failure to protect or failure to understand?

摘要

Introduction:I propose that influenza vaccine failure be defined as receipt of a properly stored and administered vaccine with the subsequent development of documented influenza. Several mechanisms of vaccine failure occur and can—sometimes in combination—lead to what is termed “vaccine failure.” Influenza vaccine failure occurs for a variety of reasons, many of which are not true failures of the vaccine (e.g., improper vaccine storage and handling).