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Seminoma with Neoplastic Meningitis Treated with Craniospinal Irradiation

机译:颅脑脊髓照射治疗精原细胞瘤合并肿瘤性脑膜炎

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摘要

Pure seminoma is a histological subtype of testicular cancer that accounts for 50% of testicular germ cell tumors. It has a very low rate of metastasis to the central nervous system, with only one previously reported case of neoplastic meningitis (cancer that has spread to the cerebrospinal fluid). Traditionally, neoplastic meningitis has an ominous prognosis when associated with primary tumors that commonly spread to the leptomeninges, like breast and lung. This article highlights a unique case of pure seminoma with neoplastic meningitis and illustrates the effectiveness of craniospinal irradiation as a treatment modality.
机译:单纯精原细胞瘤是睾丸癌的组织学亚型,占睾丸生殖细胞肿瘤的50%。它向中枢神经系统的转移率非常低,只有一例先前报道的肿瘤性脑膜炎(癌症已扩散至脑脊液)。传统上,肿瘤性脑膜炎与原发性肿瘤(通常会扩散到乳腺和肺)等原发性肿瘤相关时,预后不良。本文重点介绍了单纯精原细胞瘤伴肿瘤性脑膜炎的独特病例,并阐明了颅骨脊髓照射作为一种治疗方式的有效性。

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