Multifeature Quantification of Nuclear Properties from Images of HE-Stained Biopsy Material for Investigating Changes in Nuclear Structure with Advancing CIN Grade

摘要

Background Cervical dysplasia is a precancerous condition, and if left untreated, it may lead to cervical cancer, which is the second most common cancer in women. The purpose of this study was to investigate differences in nuclear properties of the H&E-stained biopsy material between low CIN and high CIN cases and associate those properties with the CIN grade.