The ethics of uninsured participants accessing healthcare in biomedical research: A literature review

摘要

Background/Aims:Sparse literature exists on the challenges and ethical considerations of including people with limited access to healthcare such as the uninsured and low-income in clinical research in high-income countries. However, many ethical issues should be considered with respect to working with uninsured and low-income participants in clinical research, including enrollment and retention, ancillary care, and post-trial responsibilities. Attention to the uninsured and low-income is particularly salient in the U.S. due to the high rates of uninsurance and underinsurance. Thus, we conducted a scoping review on the ethical considerations of biomedical clinical research with uninsured and low-income participants in high-income countries in order to describe what is known and to pinpoint areas of needed research on this issue.