PATH-03. PROGNOSTIC IMPORTANCE OF TUMOR GRADE IN THE POST-GENOMIC ERA

摘要

INTRODUCTIONIn the post-genomic era of glioma biology, an emerging paradigm is that the molecular and genomic features of gliomas may be more important than tumor grade in determining prognosis. Here, we analyze The Cancer Genome Atlas (TCGA) to assess whether isocitrate dehydrogenase mutation (IDHm) and mutated methylguanine methyltransferase (mMGMT) are better prognostic indicators than tumor grade.