NIMG-65. VOLUMETRIC ASSESSMENT OF PERITUMORAL EDEMA: EXCELLENT TOOL FOR DIFFERENTIAL DIAGNOSIS OF CEREBRAL GLIOMAS AND SOLITARY METASTASES

摘要

INTRODUCTIONDifferentiating cerebral gliomas from metastatic brain tumors is essential since their management and prognosis is widely different. However it is still challenging to differentiate them without pathologic confirm. In this study, we evaluated the value of tumor volume and peritumoral edema as a tool for differentiating cerebral gliomas and solitary metastases. METHOD: We retrospectively reviewed conventional MR images of 91 patients with supratentorial solitary intra-axial tumor which were pathologically confirmed by surgical procedures. Patients were classified as cerebral glioma (n=57) and metastatic tumor group (n=34). Glioma group was also subdivided as glioblastoma multiform (GBM) and non-GBM subgroups. Tumor volume, peritumoral edema volume and edema index (peritumoral edema volume/tumor volume) were analyzed by using a semi-automated 3D slicer, and compared between groups. RESULT: Cerebral glioma group showed significantly small edema volume (median 48.90ml, interquartile range[IQR] 62.12 versus 94.02ml, IQR 81.85; p<0.001) and edema index (2.01, IQR 3.15 versus 5.35, IQR 7.99; p<0.001) compared to metastatic tumor group. GBM subgroup also presented large tumor volume (median 31.45ml, IQR 40.29 versus 17.37ml, IQR 21.80; p=0.007), small edema volume (52.43ml, IQR 55.06; p=0.004) and edema index (2.03, IQR 2.16; p<0.001) than metastatic tumor group. There were no difference between non-GBM and GBM subgroups.